A Brain-Boosting Prosthesis Moves From Rats To Humans

(Wired)

If you want to get technical, the brain-booster in question is a “closed-loop hippocampal neural prosthesis.  Closed loop because the signals passing between each patient’s brain and the computer to which it’s attached are zipping back and forth in near-real-time. Hippocampal because those signals start and end inside the test subject’s hippocampus, a seahorse-shaped region of the brain critical to the formation of memories. “We’re looking at how the neurons in this region fire when memories are encoded and prepared for storage,” says Robert Hampson, a neuroscientist at Wake Forest Baptist Medical Center and lead author of the paper describing the experiment in the latest issue of the Journal of Neural Engineering

Do Older Adults Make New Brain Cells After All?

(The Guardian)

Humans continue to produce new neurons in a part of their brain involved in learning, memory and emotion throughout adulthood, scientists have revealed, countering previous theories that production stopped after adolescence. The findings could help in developing treatments for neurological conditions such as dementia.

Many new neurons are produced in the hippocampus in babies, but it has been a matter of hot debate whether this continues into adulthood – and if so, whether this rate drops with age as seen in mice and nonhuman primates.

Although some research had found new neurons in the hippocampus of older humans, a recent study scotched the idea, claiming that new neurons in the hippocampus were at undetectable levels by our late teens.

Now another group of scientists have published research that pushes back, revealing the new neurons are produced in this brain region in human adults and does not drop off with age. The findings, they say, could help in the hunt for ways to treat conditions ranging from Alzheimer’s to psychiatric problems.